What depletes the ozone layer in the atmosphere? What are the harmful effects of the depletion of ozone layer on us?

Chlorofluorocarbons used in refrigerators, air conditioners and aerosol sprays are responsible to deplete the ozone layer in the atmosphere. Ozone layer protects us from harmful ultraviolet rays of the sun. There has been a depletion of ozone layer in the layers of atmosphere which has been caused by the chlorofluorocarbons and other atmospheric pollutants. This results in increase of ultraviolet radiations at ground level which gives rise to an increased risk of skin cancer.