Assertion : Acylation of amines gives a monosubstituted product whereas alkylation of amines gives polysubstituted product.
Reason : Acyl group sterically hinders the approach of further acyl groups.
Note : In the following questions a statement of assertion followed by a statement of reason is given. Choose the correct answer out of the following choices.
Acylation is when primary and secondary amines react with acid chlorides, anhydrides and esters to give amides as products.
Alkylation is when primary and secondary amines react with alkyl halides to form a higher substituted amine. Acylation is carried out in the presence of a base stronger than the amine like pyridine which causes the shifts the equilibrium to the right side.
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