Plasmid DNA

Chromosomal DNA

•It is a naked double stranded DNA.

•It is a membrane bound double stranded DNA.

•It is a circular DNA.

•It is a linear DNA.

•It is not associated with histone protein.

•It is associated with histone protein to attain higher order of compact structure.

•Contains specific genes for the added protection of the host cell.

•Contains genes for the general functioning of the cell.

•It is found in the cytoplasm.

•It is found in the nucleoplasm of the nucleus.