| Aerobic respiration | Anaerobic respiration | 
| 1.It takes place in the presence of oxygen. | 1.it takes place in the absence of oxygen. | 
| 2.It is completed in cytoplasm and mitochondria of cells. | 2.It is completed in the cytoplasm only. | 
| 3.In involves the complete oxidation of glucose into CO2 and H2O. | 3.It involves the incomplete oxidation of glucose into CO2 and alcohol. | 
| 4.One molecule of glucose on complete oxidation releases 2870 kJ of energy. | 4.One molecule of glucose on oxidation releases 247 kJ of energy. | 
| Glycolysis | Fermentation | 
| 1. It takes place in all organisms | 1. It occurs in some microorganisms and fungi. | 
| 2. Glycolysis can function in the presence or absence of O2. | 2. Fermentation takes place only in absence of oxygen. | 
| Glycolysis | Citric Acid Cycle (Kreb’s Cycle) | 
| 1.Enzymes for glycolysis occurs inside the cytoplasm. | 1.Kreb’s cycle operates inside mitochondria because its enzymes are present in matrix. | 
| 2.Glycolysis is the first step of respiration in which glucose is completely broken down to the level of pyruvic acid. | 2.Kreb’scycle is a cyclic process, which completely breaks an active acetyl group through decarboxylation and dehydr-genation. | 
| 3.The process is common in both aerobic and anaerobic modes of respiration. | 3.It occurs only in aerobic mode of respiration. | 
| 4.Glycolysis yields 2 molecules of pyruvic acid. | 4.It degrades pyruvic acid completely into inorganic substances (CO2 + H2O). | 
| 5.It forms two molecules of NADH and two molecules of ATP for every molecule of glucose broken down. | 5.Kreb’s cycle produces four molecules of NADH2, 2 molecules of NADPH2for every two molecules or acetyl CoA oxidised by it. Two more molecules of NADH2 are liberated during conversion of pyruvic acid to Acetyl CoA. | 
| 6. No carbon dioxide is evolved in glycolysis. | 6. Carbon dioxide is evolved in kreb’s cycle. |