Hypothalamus is part of hind-brain. So it becomes the part of CNS and is responsible for maintaining the homeostasis of the body. Also, it is responsible for secreting the hormones in the human body. So because of the hypothalamus there is close coordination between nerves and hormones. Also when adrenaline is released into the blood supply of oxygen increases to the muscle which helps to run and is made of nerves. So nerves and hormones together work in case of stress.